chloropromazine hydrochlorode chloropromazine hydrochlorode

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:69-09-0

mdl number:mfcd00012654

einecs number:200-701-3

rtecs number:200-701-3

brn number:3779989

pubchem number:24277891

physical property data

1. character:white or milky white crystalline powder, hygroscopic, slightly odorous, extremely bitter in taste, easily oxidized in air or gradates to reddish brown in sunlight

2. density (g/ml,25/4℃): unsure

3. relative vapor density (g/ml,air=1): unsure

4. melting point (ºc):179-180℃（ 194-196℃ ).

5. boiling point (ºc,normal pressure): uncertain

6. boiling point (ºc, 5.2kpa): unsure

7. refractive index:not sure

8. flash point (ºc): unsure

9. specific optical rotation (º): unsure

10. autoignition point or ignition temperature (ºc): no�quantity: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine chemical bonds number of stereocenters: 0

14. number of stereocenters of uncertain chemical bonds: 0

15. number of covalent bond units: 2

properties and stability

none

storage method

keep it sealed and protected from light.

synthesis method

by2-chlorophenothiazine[92-39-7]condensation and salt formation. 1.condensation in reaction add 2- chlorophenothiazine and toluene, then add sodium hydroxide, stir and heat to reflux, remove moisture, and in 110℃ dripping1-chlorine-3-toluene solution of dimethylaminopropane, the reactant is decompressed to recover toluene to obtain chlorpromazine,c17h19cin2s,[50-53-3]. 2.salt stir and heat chlorpromazine and isopropyl alcohol until 40℃, access dry hydrogen chloride to ph 4-5, to obtain chlorpromazine hydrochloride as a salt.

purpose

has central stabilizing, antiemetic, anticonvulsant, anti- adrenaline and other effects. used to treat schizophrenia and mania. anxiety disorders, mental disorders, nausea, vomiting, etc. it can also be used for artificial hibernation and low-temperature anesthesia.

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purpose

has central stabilizing, antiemetic, anticonvulsant, anti- adrenaline and other effects. used to treat schizophrenia and mania. anxiety disorders, mental disorders, nausea, vomiting, etc. it can also be used for artificial hibernation and low-temperature anesthesia.