puromycin dihydrochloride puromycin dihydrochloride

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:58-58-2

mdl number:mfcd00067313

einecs number:200-387-8

rtecs number:au7355000

brn number:none

pubchem id:none

physical property data

1. characteristics: crystalline. hygroscopic. sensitive to light.

2. density ( g/ml,25/4℃) ： undetermined

3. relative vapor density (g/ml,air=1 ): undetermined

4. melting point ( ºc): 175.5~177.0

5. boiling point ( ºc,normal pressure): undetermined

6. boiling point ( ºc): 140-150℃（1.33×10-5kpa）

7. refractive index: undetermined

8. flashpoint (ºc): undetermined

9. specific optical rotation (º): -11

10. autoignition point or ignition temperature (ºc): not ok

11. vapor pressure (kpa,25ºc): undetermined

12. saturation vapor pressure (kpa,60ºc): undetermined

18. lower explosion limit (%,v/v): not ok

19. solubility: easily soluble in water.

toxicological data

1, acute toxicity: mice oral ld50: 720mg/kg; mouse abdominal cavity ld50: 580mg/kg; mouse intravenous ld50: .335mg/kg; guinea pig oral ld50: 600mg/kg;
guinea pig abdominal cavity ld50: 287mg/kg; guinea pig intramuscular ld50：202mg/kg
2, other multiple dose toxicity: rat abdominal tdlo: 1mg/kg/10d-i; dog intramuscular tdlo >：150mg/kg/3d-i
3 , mutagenicity: dna inhibition test: mouse abdominal cavity: 333mg/kg; mutation test system – and not otherwise specified: mouse abdominal cavity: 333mg/kg;
cytogenetic analysis: mouse peritoneal cavity: 100mg/kg

ecological data

none

molecular structure data

5. molecular property data:

1. molar refractive index: 120.56

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compute chemical data

none

properties and stability

none

storage method

this product should be sealed with argon gas0 store in a dry place below ℃ and away from light.

synthesis method

by streptococcus albicans (streptomyces.alboniger) fermentation.

purpose

biochemical research. protein synthesis inhibitor. prevents the growth of bacteria, algae, protists and mammalian cells.

s> cytogenetic analysis: mouse peritoneal cavity: 100mg/kg

ecological data

none

molecular structure data

5. molecular property data:

1. molar refractive index: 120.56

<span lang=en-us styl

compute chemical data

none

properties and stability

none

storage method

this product should be sealed with argon gas0 store in a dry place below ℃ and away from light.

synthesis method

by streptococcus albicans (streptomyces.alboniger) fermentation.

purpose

biochemical research. protein synthesis inhibitor. prevents the growth of bacteria, algae, protists and mammalian cells.