n-(2-aminoethyl)piperazine n-(2-aminoethyl)piperazine

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:140-31-8

mdl number:mfcd00005971

einecs number:205-411-0

rtecs number:tk8050000

brn number:104363

pubchem number:24890984

physical property data

1. properties: colorless or light yellow transparent liquid.

2. density (g/ml, 25/4℃): 0.9853colorless or light yellow transparent liquid. 0.989

3. relative vapor density (g/ml, air=1): undetermined

4. melting point (ºc): undetermined

5. boiling point (ºc, normal pressure): 210～230

6. boiling point (ºc, 5.2kpa): not available determined

7. refractive index: 1.500

8. flash point (ºc): 93

9. specific rotation (º): undetermined

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10. autoignition point or ignition temperature (ºc): undetermined

11. vapor pressure (kpa, 25ºc): undetermined

12. saturated vapor pressure (kpa, 60ºc): undetermined

13. heat of combustion (kj/mol): undetermined

14. critical temperature (ºc): undetermined

15. critical pressure (kpa): undetermined

16. log value of oil-water (octanol/water) partition coefficient: undetermined

17. explosion upper limit (%, v /v): undetermined

18. lower explosion limit (%, v/v): undetermined

19. solubility: soluble in water.

toxicological data

acute toxicity:

oral ld50 1500mg/kg(ckn)

2140ul/kg(rat)

skin ld50 880ul/kg(rbt)

skin irritation severe 5mg/24h(rbt)

main irritating effects:

on the skin: on the skin and mucous membranes causes corrosive effects on skin and mucous membranes

irritation.

on eyes:

strong corrosive effect

irritationthe influence of �.

sensitization: may cause sensitization through skin contact.

ecological data

general notes

do not allow this product to come into contact with groundwater, waterways or sewage systems.

water hazard class 2 (german regulation) (self-assessment via list) the substance is hazardous to water.

even extremely small amounts of product leaching into the ground can pose a hazard to drinking water

do not discharge materials into the surrounding environment without government permission.

hazardous to organic matter in the water.

molecular structure data

1. molar refractive index: 38.68

2. molar volume (cm³/mol): 129.1

3. isotonic specific volume (90.2k): 324.9

4. surface tension (dyne/cm): 40.0

5. polarizability (10^-24cm³): 15.33

compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp): -1.3

2. number of hydrogen bond donors: 2

3. number of hydrogen bond acceptors: 3

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4. number of rotatable chemical bonds: 2

5. number of tautomers: none

6. topological molecule polar surface area 41.3

7. number of heavy atoms: 9

8. surface charge: 0

9. complexity: 68.7

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine the number of chemical bond stereocenters: 0

14. number of uncertain chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

storage method

store sealed and protected from light.

synthesis method

1. this product is a by-product of the reaction of dichloroethane and ammonia to produce ethylenediamine products. raw material consumption quota: dichloroethane 2100kg/t, liquid ammonia 620kg/t, caustic soda (42%) 4143kg/t.

2.the by-product produced when dichloroethane and ammonia are reacted to produce ethylenediamine and polyamines, which are distilled and non-aminoethylpiperazine is prepared after decolorization.

purpose

1. surfactant. corrosion inhibitors. epoxy resin hardener. drug intermediates. anthelmintics.

2.used as a curing agent for epoxy resin, it is easy to use, allows a wide range of addition amounts, low shrinkage after curing, and low toxicity features. the reference dosage is 20 to 23 parts by mass, and the curing conditions are rt/3h+200℃/1h. the thermal deformation temperature of the cured product is 110~120℃. it is also used as a modifier for alkyd resin and as a raw material for manufacturing polyurethane resin, organic pigments and pharmaceuticals.