structural formula
| business number | 03wl |
|---|---|
| molecular formula | c8h10n2o3s |
| molecular weight | 214.24 |
| label |
n-(4-aminobenzenesulfonyl)acetamide, acesulfonamide sodium salt, acesulfonamide, n-(4-aminobenzenesulfonyl)acetamide |
numbering system
cas number:144-80-9
mdl number:mfcd00066501
einecs number:205-640-6
rtecs number:ac8450000
brn number:981718
pubchem number:24899803
physical property data
1. physical property data:
1. character:white crystalline powder
-bidi-font-family: tahoma”>2. melting point (ºc): 182-184ºc
3. solubility:soluble in ethanol, slightly soluble in water or ether, almost insoluble in chloroform or benzene, soluble in dilute mineral acid or alkali hydroxide solution.
toxicological data
2. toxicological data:
1, acute toxicity: rat intravenous ld50: 6600 mg/kg;
mouse oral ld50: 16500 mg/kg;
mouse abdominal cavity ld50: 606 mg/kg.
2. reproductive toxicity: rattdlo: 10 gm/kg
ecological data
3. ecological data:
other harmful effect: this substance may be harmful to the environment, and special attention should be paid to water bodies.
molecular structure data
5. molecular property data:
1. molar refractive index:52.21
2. molar volume (m3/mol):155.9
3. isotonic specific volume (90.2k):424.7
4. surface tension (dyne/cm):55.0
5. polarizability(10-24cm3）：20.69
compute chemical data
1. reference value for hydrophobic parameter calculation (xlogp): none
2. number of hydrogen bond donors: 2
3. number of hydrogen bond acceptors: 4
4. number of rotatable chemical bonds: 2
5. number of tautomers: 2
6. topological molecule polar surface area 97.6
7. number of heavy atoms: 14
8. surface charge: 0
9. complexity: 299
10. number of isotope atoms: 0
11. determine the number of atomic stereocenters: 0
12. uncertain number of atomic stereocenters: 0
13. determine the number of chemical bond stereocenters: 0
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
stable under normal temperature and pressure. 2. moore volume (m3/mol ): 155.9
3. isotonic specific volume (90.2k):424.7
4. surface tension (dyne/cm):55.0
5. polarizability(10-24cm3）：20.69
compute chemical data
1. reference value for hydrophobic parameter calculation (xlogp): none
2. number of hydrogen bond donors: 2
3. number of hydrogen bond acceptors: 4
4. number of rotatable chemical bonds: 2
5. number of tautomers: 2
6. topological molecule polar surface area 97.6
7. number of heavy atoms: 14
8. surface charge: 0
9. complexity: 299
10. number of isotope atoms: 0
11. determine the number of atomic stereocenters: 0
12. uncertain number of atomic stereocenters: 0
13. determine the number of chemical bond stereocenters: 0
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
stable under normal temperature and pressure.
storage method
save at 0-6ºc.
synthesis method
obtained by acidification of sodium sulfonamide acetate. dissolve sodium sulfonamide acetate in water and use 5%hydrochloric acid is adjusted to ph3.8-4 to precipitate sulfonamide acetyl. filter, wash and dry to get the finished product.
purpose
medicine, used to treat conjunctivitis, trachoma and other eye infections.
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storage method
save at 0-6ºc.
synthesis method
obtained by acidification of sodium sulfonamide acetate. dissolve sodium sulfonamide acetate in water and use 5%hydrochloric acid is adjusted to ph3.8-4 to precipitate sulfonamide acetyl. filter, wash and dry to get the finished product.
purpose
medicine, used to treat conjunctivitis, trachoma and other eye infections.
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