(4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6-diyl) preparation of bistrimethyltin_kain industrial additives

background and overview^[1]

(4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6- diyl) bistrimethyltin can be used as a pharmaceutical synthesis intermediate. if you inhale (4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6-bis (bit) bistrimethyltin, please move the patient to fresh air; if the skin comes into contact, take off contaminated clothes, wash the skin thoroughly with soap and water, if you feel uncomfortable, seek medical treatment; if the eyes come into contact, seek medical attention separate eyelids, rinse with running water or saline, and seek medical attention immediately; if ingested, rinse mouth immediately, do not induce vomiting, and seek medical attention immediately.

preparation^[1]

(4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6- the preparation of diyl)bistrimethyltin is as follows: step 1: 1) use 3-chloro-thiophene as raw material, thf as solvent, add lda, react at 0°c for 2 hours; then add 2-ethylhexyl bromide, 60°c, overnight. (2) dissolve 3-chloro-2-(2-ethylhexyl)-thiophene prepared in step 1 in thf, add n-buli, and react at 0°c for 2 hours; add benzo[1,2-b:4 , 5-b’]bithiophene-4,8-dione, react at 50°c for 2 hours; add sncl2·2h2o, hcl, room temperature, and then 50°c overnight. (3) add lda and thf to the intermediate prepared in step 2 and react at -78°c for 4 hours; add sn(ch3)3cl and heat from -78°c to room temperature overnight to prepare (4,8-di(4) -chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6-diyl)bistrimethyltin

apply^[1]

(4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]dithiophene-2,6- diyl)bistrimethyltin can be used to synthesize the following compounds:

to (4,8-bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b4,5-b’]bithiophene-2,6 -diyl)bistrimethyltin is prepared by adding tt-f, adding pd(pph3)4, dissolving in anhydrous toluene/dmf, and reacting at 120°c.

main reference materials

[1] rination of side chains: a strategy for achieving a high open circuit voltage over 1.0 v in benzo[1,2-b:4,5-b#]dithiophene-based non-fullerene solar cells