tolbutamide tolbutamide

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:64-77-7

mdl number:mfcd00027169

einecs number:200-594-3

rtecs number:ys4550000

brn number:1984428

pubchem number:24277742

physical property data

1. character:white crystalline powder. odorless and tasteless

2. density (g/ml,25/4℃): unsure

3. relative vapor density (g/ml,air=1): unsure

4. melting point (ºc):128 -130

5. boiling point (ºc,normal pressure): uncertain

6. boiling point (ºc, 5.2kpa): unsure

7. refractive index:not sure

8. flash point (ºc): unsure

9. specific optical rotation (º): unsure

10. autoignition point or ignition temperature (ºc): unsure

11. vapor pressure (kpa,25ºc): unsure

12. <span style="font-size: 9pt; font-family: 宋体; mso-ascii-font-family: arial; mso-hansi-font-fa): 583.5

4. surface tension (dyne/cm):42.7

5. polarizability（10^-24cm³): 28.05

compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp): none

2. number of hydrogen bond donors: 2

3. number of hydrogen bond acceptors: 3

4. number of rotatable chemical bonds: 5

5. number of tautomers: 3

6. topological molecule polar surface area 83.6

7. number of heavy atoms: 18

8. surface charge: 0

9. complexity: 354

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine the number of chemical bond stereocenters: 0

14. number of uncertain chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

none yet

storage method

this product should be sealed in 0℃save the following in a dry place and away from light.

synthesis method

prepared from the condensation of butyl isocyanate and p-toluenesulfonamide, or from the condensation of n-butylamine hydrochloride and toluenesulfonylurea become.

purpose

a hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.

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purpose

a hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.