xanthene -9-carboxylic acid xanthene -9-carboxylic acid

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:82-07-5

mdl number:mfcd00005059

einecs number:201-394-9

rtecs number:none

brn number:174414

pubchem number:24902145

physical property data

1. character: solid.

2. density (g/ml,25/4℃): unsure

3. relative vapor density ( g/ml,air =1): unsure

4. melting point (ºc): 217(decomposition)

5. boiling point (ºc,normal pressure): unsure

6. boiling point (ºc,5.2kpa): unsure

7. refractive index: uncertain

8. flashpoint (ºc): unsure

9. specific optical rotation (º): unsure

10. autoignition point or ignition temperature (ºc): unsure

11. vapor pressure (kpa,25ºc): unsure

12. saturated vapor pressure (0

11. not sure number of atomic stereocenters:0

12. determine chemical bonds number of stereocenters:0

13. not sure number of stereocenters of chemical bonds:0

14. covalent number of key units:1

properties and stability

none yet

storage method

save sealed in a cool, dry place.

synthesis method

xanthenol, the mixture of sodium cyanide, glacial acetic acid, ethanol and water is heated in a closed reaction tank and slowly raised to 95℃, pressure0.1-0.2mpa,reaction6h, got9-cyanoxanthene. then reflux with alkali solution20h, and then acidified with hydrochloric acid to obtain xanthene-9-carboxylic acid.

purpose

intermediate of the anticholinergic drug propantheline bromide.

style=”font-size: 9pt; font-family: arial; mso-font-kerning: 0pt”>9-cyanoxanthene. then reflux with alkali solution20h, and then acidified with hydrochloric acid to obtain xanthene-9-carboxylic acid.

purpose

intermediate of the anticholinergic drug propantheline bromide.