application of di-p-tolylmethane_kain industrial additive

background and overview^[1][2]

di-p-tolylmethane is a compound that can be used as a high-boiling organic solvent.

preparation^[2]

general/typical procedure: to a solution of diaryl ketone (10.0 mmol) in methanol (20 ml) was added pd/c (20%, 200 mg). the reaction mixture was stirred at room temperature under a hydrogen atmosphere for 16 hours. the solvent was removed under reduced pressure and the product was purified by flash column chromatography on silica gel using pentane as eluent. for di-p-tolylmethane, refer to the above method, yield: 94%, white solid. ¹h nmr (600mhz, cdcl₃) δ (ppm) 7.02-6.99 (m, 8h), 3.83 (s, 2h), 2.23 (s, 6h). ¹³ch nmr (150mhz, cdcl₃) δ (ppm) 138.3, 135.4, 129.1, 128.7, 41.1, 21.0. ms (ei): m/z = 196 (m⁺, 77), 181 (100), 105 (9), 77 (10).

apply^[1]

a method for preparing 2,4-diaminobenzenesulfonic acid, which method includes the following steps: reacting m-phenylenediamine and sulfuric acid or fuming sulfuric acid in a solvent in a temperature range of 140 to 250°c, to prepare 2,4-diaminobenzenesulfonic acid, the solvent is one or more of the following solvents: an inorganic solvent selected from phosphoric acid or polyphosphoric acid and an organic solvent with a normal pressure boiling point above 140°c. the organic solvent is one or more selected from the following solvents: xylene, trimethylbenzene, cumene, isobutylbenzene, tert-butylbenzene, cumene, naphthalene, methylnaphthalene, tetralin, diphenylmethane, di-p-tolylmethane, dimethylchlorobenzene, trimethylchlorobenzene, dichlorobenzene, trichlorobenzene, bromobenzene, chlorotoluene, dichlorotoluene, bromotoluene, xylene bromobenzene, nitrobenzene, nitrotoluene, nitroethylbenzene, nitroxylene, trimethylnitrobenzene, nitrochlorobenzene, acetophenone, nonane, undecane, paraffin, chlorinated paraffin , high temperature kerosene, thermal oil, tetrabromoethane, trichloropropane, tetrabromobutane, cyclohexanone, sulfolane, succinonitrile and adiponitrile.

main reference materials

[1] [chinese invention, chinese invention authorization] cn200610029051.2 synthesis method of 2,4-diaminobenzenesulfonic acid and its salt

[2] cheng y , dong w , wang l , et al. iron-catalyzed hetero-cross-dehydrogenative coupling reactions of sulfoximines with diarylmethanes: a new route to n-alkylated sulfoximines[j]. organic letters, 2015, 45(37):2000.