2,6-diaminopyridine

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:141-86-6

mdl number:mfcd00006329

einecs number:205-507-2

rtecs number:us7570000

brn number:108513

pubchem id:none

physical property data

1. physical property data:

1.character: flake crystal

2.flash point (℃): 155

3.melting point (℃): 121.5

4.boiling point (ºc): 285

toxicological data

2. toxicological data:

1, acute toxicity: mouse abdominal cavity ld50: 100 mg /kg

mouse intravenous ld50: 56 mg/kg.

ecological data

3. ecological data:

1. other harmful effects: this substance may be harmful to the environment, and special treatment should be given to water bodies. notice.

molecular structure data

5. molecular property data:

compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp): 0.2

2. number of hydrogen bond donors: 2

3. number of hydrogen bond acceptors: 3

4. number of rotatable chemical bonds: 0

5. number of tautomers: 5

6. topological molecule polar surface area 64.9

7. number of heavy atoms: 8

8. surface charge: 0

9. complexity: 66.1

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine the number of chemical bond stereocenters: 0

14. number of uncertain chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

stable under normal temperature and pressure.

incompatible materials:strong oxidizing agent

storage method

store sealed and away from light.

synthesis method

pyridine or2-aminopyridines are aminated under more intense conditions.

purpose

1.2,6- diaminopyridine is currently mainly used in the production of an analgesic abroad——phenazopyridine [cas no.94 -78-0], said to relieve pain, burning and discomfort caused by conditions such as urinary tract infections. the drug is a prescription drug in the united states, an over-the-counter drug in canada, and has not yet been produced in china. the trade names of this drug in the united states are: azo-standard, baridium, eridium, geridium, phenazodine, pyridiate, pyridium, urodine, urogesic, viridium; the trade names of this drug in canada are: phenazo, pyridium.

2.for coupling diazo compounds.

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compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp): 0.2

2. number of hydrogen bond donors: 2

3. number of hydrogen bond acceptors: 3

4. number of rotatable chemical bonds: 0

5. number of tautomers: 5

6. topological molecule polar surface area 64.9

7. number of heavy atoms: 8

8. surface charge: 0

9. complexity: 66.1

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine the number of chemical bond stereocenters: 0

14. number of uncertain chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

stable under normal temperature and pressure.

incompatible materials:strong oxidizing agent

storage method

store sealed and away from light.

synthesis method

pyridine or2-aminopyridines are aminated under more intense conditions.

purpose

1.2,6- diaminopyridine is currently mainly used in the production of an analgesic abroad——phenazopyridine [cas no.94 -78-0], said to relieve pain, burning and discomfort caused by conditions such as urinary tract infections. the drug is a prescription drug in the united states, an over-the-counter drug in canada, and has not yet been produced in china. the trade names of this drug in the united states are: azo-standard, baridium, eridium, geridium, phenazodine, pyridiate, pyridium, urodine, urogesic, viridium; the trade names of this drug in canada are: phenazo, pyridium.

2.for coupling diazo compounds.