tetrahydrofolate

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:135-16-0

mdl number:mfcd00135583

einecs number:205-181-1

rtecs number:ma0600800

brn number:9238187

pubchem number:24900106

physical property data

none

toxicological data

other multi-dose data:

rat subcutaneous tdlo: 18 gm/kg/5w-i

reproduction data:

big female rat subcutaneous tdlo for 8-14 days after pregnancy: 70mg/kg

little female mouse after pregnancy 7-13 days subcutaneously tdlo: 70mg/kg

ecological data

none

molecular structure data

sub-property data:

1, molar refractive index：107.81

2, molar volume（m³/mol): 261.3

3, isotonic specific volume（90.2k）：783.3

4, surface tension（3.0 dyne/cm span>): 80.6

5, polarizability（ 0.5 10^-24cm³): 42.74

compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp):-0.6

2. number of hydrogen bond donors: 8

3. number of hydrogen bond acceptors: 11

4. number of rotatable chemical bonds: 9

5. number of tautomers: 27

6. topological molecular polar surface area (tpsa):207

7. number of heavy atoms: 32

8. surface charge: 0

9. complexity: 834

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 1

12. the number of uncertain atomic stereocenters: 1

13. determine the number of stereocenters of chemical bonds: 0

14. uncertain number of chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

crystallize. hygroscopic. sensitive to light

storage method

seal with argon gas and store in a dry place below 0℃ and away from light.

synthesis method

none

purpose

biochemical research.

so-bidi-font-family: arial”>determine the number of stereocenters of chemical bonds: 0

14. uncertain number of chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

crystallize. hygroscopic. sensitive to light

storage method

seal with argon gas and store in a dry place below 0℃ and away from light.

synthesis method

none

purpose

biochemical research.