1-naphthylthiourea

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:86-88-4

mdl number:mfcd00041824

einecs number:201-706-3

rtecs number:yt9275000

brn number:778118

pubchem number:24868783

physical property data

1. properties: white prismatic crystals are obtained from alcohol. odorless, bitter, and highly toxic.

2. density (g/ml, 25/4℃): undetermined

3. relative vapor density (g/ml, air=1): undetermined

4. melting point (ºc): 198℃

5. boiling point (ºc, normal pressure): undetermined

6. boiling point (ºc, 5.2kpa): undetermined determined

7. refractive index: undetermined

8. flash point (ºc): undetermined

9. specific rotation (º): undetermined

10. autoignition point or ignition temperature (ºc): undetermined

11. vapor pressure (kpa, 25ºc): undetermined

12. saturation vapor pressure (kpa, 60ºc): undetermined

13. heat of combustion (kj/mol): undetermined

14. critical temperature (ºc): undetermined

15. critical pressure (kpa): undetermined

16. log value of oil-water (octanol/water) partition coefficient: undetermined

17. explosion upper limit (% , v/v): undetermined

18. lower explosion limit (%, v/v): undetermined 19. solubility: solubility in water at 25°c is 0.06g/100ml, solubility in propanol it is 2.43g/100ml and is easily soluble in hot ethanol.

toxicological data

norwegian rat acute oral ld₅₀ is 6-8mg/kg > dog oral ld₅₀ is 380mg/ kg, the oral ld₅₀ for monkeys is 4250 mg/kg, the minimum lethal dose for humans is 588 mg/kg, and the ld₅₀ for cats is 100 mg/kg.

ecological data

none yet

molecular structure data

1. �er refractive index: 64.52

2, molar volume (cm³/mol): 151.6

3, isotonic specific volume (90.2k): 445.5

4. surface tension (dyne/cm): 74.4

5. polarizability (10^-24cm³) ：25.58

compute chemical data

1. reference value for hydrophobic parameter calculation (xlogp): none

2. number of hydrogen bond donors: 2

3. number of hydrogen bond acceptors: 1

4. number of rotatable chemical bonds: 1

5. number of tautomers: 3

6. topological molecule polar surface area 70.1

7. number of heavy atoms: 14

8. surface charge: 0

9. complexity: 217

10. number of isotope atoms: 0

11. determine the number of atomic stereocenters: 0

12. uncertain number of atomic stereocenters: 0

13. determine the number of chemical bond stereocenters: 0

14. number of uncertain chemical bond stereocenters: 0

15. number of covalent bond units: 1

properties and stability

none yet

storage method

this product should be kept sealed, dry and protected from light.

synthesis method

1.antuo is produced by the reaction of α-naphthylamine and ammonium thiocyanate.
2.preparation method two

3.preparation method three

purpose

thiocarbamide acute rodenticide. it has strong selectivity and is mainly used to control rattus norvegicus and yellow-haired rat. it has low toxicity to other rat species. this agent has a strong stomach poisoning effect and can also damage the respiratory system of rats. generally, death occurs within 6 to 72 hours after eating. antuo has good palatability and is ideal for initial use. however, after ingestion of sub-lethal doses, it will develop strong drug resistance. the drug resistance can be increased by 7 to 50 times, and it will develop cross-resistance to other thiourea derivatives. it is advisable to prepare poisonous baits to control rodents. the active ingredients of poisonous baits are 0.5% to 2%. the preparation method is the same as zinc phosphide rodenticide. example 1: 0.5% antuo carrot poison bait (or use fruits or vegetables instead), place 2 to 3 piles in each room, each pile contains 10 to 20g of poison bait, and recover the remaining poison bait after 3 days. example 2: 1 part antuo raw powder, 1 part fish bone meal, 1 part edible oil, 97 parts cornmeal, mix evenly, then add appropriate amount of water to form a dough, and make poison bait pills the size of soybeans, put 2 to 3 piles in each room. 10-20g per pile is very effective in controlling rattus norvegicus. it can also be made into 2% safe wheat poison bait for use.