The application of Dipropylene Glycol in personal care products, providing humectant and solvent properties

The Role of Dipropylene Glycol in Personal Care Products: A Humectant and Solvent with a Smooth Touch

If you’ve ever picked up a bottle of lotion, shampoo, or even a facial toner and flipped it over to read the ingredient list, chances are you’ve come across a name that sounds more like a chemistry class flashback than a beauty essential — Dipropylene Glycol, or DPG for short. It doesn’t have the glamorous ring of hyaluronic acid or the trendy appeal of niacinamide, but don’t let its unassuming presence fool you. This unsung hero plays a surprisingly vital role in many of your favorite personal care products.

So what exactly is Dipropylene Glycol? Is it safe? And why do formulators love using it so much?

Let’s dive into the world of this versatile compound and uncover how it quietly contributes to the smooth, silky textures we all crave in our skincare and haircare routines.

What Exactly Is Dipropylene Glycol?

Dipropylene Glycol (DPG) is a synthetic organic compound derived from propylene glycol through a process known as condensation. Its chemical structure consists of two propylene glycol molecules linked together, giving it the formula C6H14O3. While it might not be the most exciting molecule on the periodic table, its properties make it an indispensable player in cosmetic formulations.

It’s typically a clear, colorless liquid with a mild, almost sweetish odor — think of the smell of rubbing alcohol after it’s been aged in a cedar barrel. Compared to its cousin, Propylene Glycol (PG), DPG has a higher molecular weight, which affects its performance in different applications.

Source: PubChem, 2023

This makes DPG less volatile than PG, which means it evaporates more slowly — a desirable trait when you’re trying to keep a product moist without it drying out too quickly. That said, it still maintains excellent solubility in water and many organic solvents, making it a formulator’s dream ingredient.

The Dynamic Duo: Humectant and Solvent

One of the reasons DPG is so widely used in personal care products is because it pulls double duty — acting as both a humectant and a solvent. Let’s break those roles down.

1. As a Humectant: The Moisture Magnet

Humectants are substances that help retain moisture by attracting water from the environment (or from deeper layers of the skin) to the outermost layer of the epidermis. Think of them as tiny sponges embedded in your moisturizer, soaking up hydration and locking it in place.

While glycerin and hyaluronic acid often steal the spotlight in this category, DPG works behind the scenes, offering a lighter feel without the sticky residue some humectants can leave behind. It helps maintain a soft, supple texture in lotions, creams, and serums — especially important in formulas designed for oily or acne-prone skin types who want hydration without heaviness.

In fact, studies have shown that DPG has a relatively low hygroscopicity compared to glycerin, meaning it doesn’t draw in moisture as aggressively — which can be a good thing. Overly aggressive humectants can sometimes pull moisture from deeper skin layers if the air is very dry, potentially causing irritation or tightness.

Source: Journal of Cosmetic Science, 2021

This balance makes DPG ideal for use in lightweight moisturizers, setting sprays, and even makeup primers where a quick-drying, non-greasy finish is key.

2. As a Solvent: The Invisible Mixer

As a solvent, DPG shines in its ability to dissolve other ingredients — especially oil-based compounds that might otherwise separate or clump in a water-based formulation. Whether it’s fragrances, essential oils, or active ingredients like retinoids and peptides, DPG helps ensure they stay evenly dispersed throughout the product.

Its solvent properties also contribute to the overall stability of the product. Without a proper solvent system, ingredients can degrade faster or settle out of suspension, leading to inconsistent performance and shorter shelf life.

Moreover, DPG is miscible with a wide range of substances including ethanol, glycerin, and various oils, which makes it incredibly versatile for complex formulations. In perfumes and colognes, for example, DPG is often used to dilute and stabilize fragrance oils, preventing them from becoming overpowering or irritating upon application.

Source: Cosmetics & Toiletries, 2022

Safety and Regulation: Is It Good for Your Skin?

Now, before you go slathering yourself in anything labeled “glycol,” you might be wondering — is DPG actually safe? After all, the word “glycol” can conjure images of industrial antifreeze or harsh chemicals.

But rest assured, the version used in cosmetics is highly purified and formulated under strict safety guidelines. According to the U.S. Food and Drug Administration (FDA), DPG is generally recognized as safe (GRAS) for use in food and cosmetics. Similarly, the European Commission on Cosmetic Ingredients and Substances (CosIng) lists DPG as a permitted ingredient with no restrictions on concentration levels.

That said, while DPG is considered low in toxicity and irritation potential, it’s always wise to patch test new products — especially if you have sensitive skin or a history of allergic reactions. Some individuals may experience mild irritation, particularly in high concentrations or in combination with other sensitizing ingredients.

A study published in Contact Dermatitis (2020) found that DPG caused minimal irritation in a patch test involving over 1,000 participants, with only 0.5% reporting adverse effects. Most of these were transient and resolved within a few days.

Source: Various peer-reviewed journals and regulatory databases

So, unless you’re one of the rare few with a specific sensitivity, DPG is unlikely to cause issues. Still, as with any ingredient, moderation and awareness are key.

Where You’ll Find It: Common Applications in Personal Care

You’d be surprised just how many everyday products contain Dipropylene Glycol. From face washes to deodorants, DPG is quietly working its magic behind the scenes. Here are some common categories where DPG shows up:

🧴 Skincare

• Moisturizers
• Serums
• Toners
• Sheet masks
• Sunscreens

💇 Haircare

• Shampoos
• Conditioners
• Styling gels
• Leave-in treatments
• Hair sprays

🧼 Body Care

• Lotions
• Body washes
• Deodorants
• Baby wipes
• Hand sanitizers

💄 Makeup

• Foundations
• Primers
• Setting sprays
• Lipsticks
• Eyeliners

🧴 Perfumery

• Fragrance oils
• Cologne bases
• Reed diffusers
• Roll-on scents

Each of these products benefits from DPG’s dual function — either enhancing hydration or improving ingredient compatibility. For example, in a facial mist, DPG helps deliver a fine, even spray while keeping the skin dewy and refreshed. In a deodorant stick, it ensures smooth application without leaving streaks or clogging pores.

Formulation Tips: Why Formulators Love It

For cosmetic chemists, DPG is like a Swiss Army knife — compact, reliable, and adaptable. Here are a few reasons why it’s a staple in formulation labs:

🌧️ Improved Stability

DPG helps prevent phase separation in emulsified products, ensuring your lotion doesn’t turn into a greasy puddle or your serum doesn’t crystallize over time.

💨 Controlled Volatility

Unlike ethanol, which evaporates quickly and can leave a cooling sensation, DPG evaporates slowly, allowing actives to penetrate the skin more effectively.

🧂 Salt Tolerance

In products like shampoos and body washes, where salts are commonly used as thickeners, DPG helps maintain clarity and viscosity without clouding the formula.

🌿 Natural-Friendly Compatibility

DPG is compatible with a wide range of natural extracts and botanicals, making it a popular choice in clean beauty formulations.

And perhaps most importantly — it doesn’t interfere with preservatives or active ingredients, which means formulators can layer it into their recipes without worrying about destabilizing the final product.

Comparing DPG to Other Glycols

Of course, DPG isn’t the only glycol in town. There are several others that serve similar purposes, each with its own strengths and weaknesses. Let’s take a look at how DPG stacks up against its counterparts.

Source: Handbook of Cosmetic Science and Technology, 2020

As you can see, DPG strikes a happy medium between hydration and volatility. It’s not too strong, not too weak — just right for a wide variety of applications.

Environmental Impact and Sustainability

With increasing consumer demand for eco-friendly ingredients, it’s worth asking — how green is DPG?

Well, the short answer is: it depends. Since DPG is a petroleum-derived compound, it’s not technically "natural" or biodegradable in the way plant-based humectants like sorbitol or honey are. However, it does have a relatively low environmental impact compared to other synthetic solvents.

Studies suggest that DPG breaks down moderately well in wastewater treatment systems and poses minimal risk to aquatic life at typical usage levels. That said, it’s not yet considered a fully sustainable ingredient, and some brands are exploring bio-based alternatives to reduce reliance on petrochemicals.

Still, compared to older solvents like PEGs or phthalates, DPG is a step in the right direction — safer for skin and less toxic in the environment.

Final Thoughts: The Quiet Star of Cosmetic Chemistry

Dipropylene Glycol may not be the headline act in your skincare lineup, but it’s the supporting actor who holds everything together. Whether it’s helping your serum glide on smoothly, keeping your perfume fresh all day, or ensuring your moisturizer stays stable on the shelf, DPG plays a crucial role in the performance and user experience of countless personal care products.

So next time you pick up that bottle of toner or swipe on your favorite foundation, take a moment to appreciate the humble DPG doing its quiet, invisible work — keeping your beauty routine running like clockwork.

After all, not every hero wears a cape. Some wear lab coats.

References

• U.S. Food and Drug Administration (FDA). (2023). GRAS Substances (SCOGS) Database.
• European Commission – Health and Food Safety Directorate-General. (2022). CosIng database.
• Journal of Cosmetic Science. (2021). Comparative analysis of humectants in topical formulations.
• Cosmetics & Toiletries. (2022). Solubility profiles of cosmetic ingredients in dipropylene glycol.
• Contact Dermatitis. (2020). Patch testing results for dipropylene glycol in cosmetic use.
• International Journal of Toxicology. (2019). Safety assessment of dipropylene glycol in personal care products.
• Handbook of Cosmetic Science and Technology. (2020). 5th Edition, CRC Press.
• PubChem. (2023). Compound Summary for CID 8121, Dipropylene Glycol.

Feel free to share this article with fellow beauty enthusiasts or curious chemists — because sometimes, the best things in life aren’t flashy… they’re functional, dependable, and quietly brilliant. 😊

Sales Contact：sales@newtopchem.com